I have just gone through bilateral breast cancer surgery and in the process had the gene mutation testing completed. I discovered that I carry a BRIP1 gene mutation which research says puts me at a high risk for ovarian cancer. I met with a surgeon who said the newest research is putting the BRIP1 gene mutation 3rd in order of gene mutations that carry the biggest risk. The general consensus from my breast cancer surgeon, the new surgeon, and my oncologist is that I should do a prophylactic bilateral oopherectomy. I am pre-menopausal and very worried about all of the research I have read about dementia, osteoporosis, and other worrying side effects of having your ovaries removed.
I think I'm coming here to find out if anyone else tested positive for the BRIP1 gene mutation and also to help understand the side effects I will face. I cannot have hormone replacement therapy because my breast cancer was estrogen receptor positive.
Is worrying about the side effects ridiculous in the face of a gene mutation that increases my risk of ovarian cancer?