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HU5F9-GR with Avelumab clinical trial

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Hello,

I'm a new member and only just found this forum. My mom has been battling a second round of Ovarian since 2016 (was previously 10 years in remission). After running through all the platin-based chemos, her cancer is now considered platinum resistant. Doctor is out of options other than putting her on Tamoxifen, but CA-125 numbers are going up (on it for about a month). I'm also having my mom take curcumin. (on it for a couple of weeks).

We are looking into the clinical trial above and I wanted to know if anyone else has had any experience good or bad with either drug or the combined trial. I know the Avelumab phase III trial for Ovarian cancer was ended (failed to obtain progression free survival) but it is being looked at again in combo with this new drug.

 
We're trying to decide if we should give the Tamoxifen longer to work or pursue the trial. Not able to do both.
 
Many thanks!
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